Notify your health care provider Should you be Expecting or Imagine you could be pregnant. During pregnancy, this products will not be proposed. It may harm an unborn toddler. Speak to your health practitioner regarding the threats and great things about this medication. See also Warning area.

This medication may possibly make you additional sensitive into the sun. Limit your time and efforts within the Sunlight. Steer clear of tanning booths and sunlamps. Use sunscreen and put on protecting apparel when outdoor. Notify your physician straight away if you get sunburned or have skin blisters/redness.

Life-threatening respiration issues (respiratory depression). Promethazine Hydrochloride and Codeine Phosphate Oral Alternative could potentially cause respiration complications (respiratory depression) that could occur Anytime during remedy and can cause Loss of life. Your possibility of respiration problems is finest once you to start with start off using Promethazine Hydrochloride and Codeine Phosphate Oral Solution, are having other medicines that may cause breathing troubles, have particular lung complications, are aged or have particular other health conditions.

The concomitant utilization of Promethazine HCl and Codeine Phosphate Oral Option with all cytochrome P450 3A4 inducers or discontinuation of a cytochrome P450 3A4 inhibitor could cause lower codeine ranges, greater norcodeine levels, and less metabolism via 2D6 with resultant reduced morphine amounts.

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Greater tension in your head (amplified intracranial force). Avoid the use of Promethazine Hydrochloride and Codeine Phosphate Oral Option For those who have a head injury or happen to be told that you've got variations inside the tissue of the brain (brain lesions) or enhanced strain with your head.

Consider this medication by mouth with or with no food as directed by your doctor, ordinarily each and every four to 6 hours as essential. This medication may be taken with meals if stomach upset occurs. Consume lots of fluids whenever you use this medication Unless of course usually directed by your medical doctor.

Labor or Shipping and delivery Opioids cross the placenta and could generate respiratory melancholy and psycho-physiologic consequences in neonates. An opioid antagonist, such as naloxone, needs to be accessible for reversal of opioid-induced respiratory depression in the neonate.

Uncomfortable side effects that usually usually do not involve health care interest (report back to your treatment group if they carry on or are bothersome):

Retailer at home temperature far from light-weight and humidity. Usually do not shop in the bathroom. Don't freeze. Maintain all drugs away from youngsters and pets.

Postmarketing conditions of respiratory depression, which include fatalities are claimed with utilization of promethazine in pediatric individuals.

In advance of utilizing this medication, women of childbearing age need to talk to their doctor(s) regarding the risks and Positive aspects. Tell your medical doctor When you are pregnant or Believe you may be pregnant. Through pregnancy, this medication is not proposed. It may well a little bit raise the threat of start defects if utilised over the very first two months of pregnancy. Also, applying it for a long time or in superior doses close to the Promethazine codeine syrup anticipated shipping and delivery date could hurt the unborn baby.

The procedure of overdosage with promethazine and codeine is actually symptomatic and supportive. Only in cases of maximum overdosage or unique sensitivity do essential indications including respiration, pulse, blood pressure level, temperature, and EKG have to be monitored. Activated charcoal orally or by lavage could be provided, or sodium or magnesium sulfate orally to be a cathartic. Notice need to be supplied towards the reestablishment of adequate respiratory Trade through provision of a patent airway and establishment of assisted or managed air flow.